2101524-34-7

2101524-34-7 structure

Name: JNJ-64264681
Chemical Name: JNJ-64264681
CAS Number: 2101524-34-7
Molecular Formula: C₂₇H₃₀N₆O₃S
Molecular Weight: 518.63
Catalog: Signaling Pathways Protein Tyrosine Kinase/RTK Btk
Create Date: 2023-10-14 15:45:11
Modify Date: 2025-09-21 09:54:48
JNJ-64264681 is a potent, orally active, selective and irreversible covalent BTK inhibitor. JNJ-64264681 exhibits good pharmacokinetic characteristics and can be used for cancer and autoimmune diseases research[1].

Name	JNJ-64264681

Description	JNJ-64264681 is a potent, orally active, selective and irreversible covalent BTK inhibitor. JNJ-64264681 exhibits good pharmacokinetic characteristics and can be used for cancer and autoimmune diseases research[1].
Related Catalog	Research Areas >> Cancer Research Areas >> Inflammation/Immunology Signaling Pathways >> Protein Tyrosine Kinase/RTK >> Btk
References	[1]. Mark S Tichenor, et al. Discovery of JNJ-64264681: A Potent and Selective Covalent Inhibitor of Bruton's Tyrosine Kinase. J Med Chem. 2022 Nov 10;65(21):14326-14336.

Molecular Formula	C₂₇H₃₀N₆O₃S
Molecular Weight	518.63