2861190-30-7

2861190-30-7 structure

Name: Mtb-IN-2
Chemical Name: Mtb-IN-2
CAS Number: 2861190-30-7
Molecular Formula: C₁₇H₁₂N₂O₄
Molecular Weight: 308.29
Catalog: Signaling Pathways Anti-infection Bacterial
Create Date: 2023-10-02 21:21:20
Modify Date: 2024-02-04 08:49:58
Mtb-IN-2 (compound 10c) is an antimicrobial agent against Mycobacterium tuberculosis (Mtb), without cytotoxicity. Mtb-IN-2 significantly decreases colony-forming units (CFU) in spleen of murine tuberculosis models, and distinguishes both drug-sensitive and drug-resistant Mtb H37Rv strains. Mtb-IN-2 affects methionine metabolism but not folate pathway directly.

Name	Mtb-IN-2

Description	Mtb-IN-2 (compound 10c) is an antimicrobial agent against Mycobacterium tuberculosis (Mtb), without cytotoxicity. Mtb-IN-2 significantly decreases colony-forming units (CFU) in spleen of murine tuberculosis models, and distinguishes both drug-sensitive and drug-resistant Mtb H37Rv strains. Mtb-IN-2 affects methionine metabolism but not folate pathway directly.
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial
References	[1]. Nawrot DE, et al. Antimycobacterial pyridine carboxamides: From design to in vivo activity. Eur J Med Chem. 2023 Oct 5;258:115617.

Molecular Formula	C₁₇H₁₂N₂O₄
Molecular Weight	308.29