Mtb-IN-2

Modify Date: 2025-08-26 17:21:26

Mtb-IN-2 Structure
Mtb-IN-2 structure
Common Name Mtb-IN-2
CAS Number 2861190-30-7 Molecular Weight 308.29
Density N/A Boiling Point N/A
Molecular Formula C17H12N2O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Mtb-IN-2


Mtb-IN-2 (compound 10c) is an antimicrobial agent against Mycobacterium tuberculosis (Mtb), without cytotoxicity. Mtb-IN-2 significantly decreases colony-forming units (CFU) in spleen of murine tuberculosis models, and distinguishes both drug-sensitive and drug-resistant Mtb H37Rv strains. Mtb-IN-2 affects methionine metabolism but not folate pathway directly.

 Names

Name Mtb-IN-2

 Mtb-IN-2 Biological Activity

Description Mtb-IN-2 (compound 10c) is an antimicrobial agent against Mycobacterium tuberculosis (Mtb), without cytotoxicity. Mtb-IN-2 significantly decreases colony-forming units (CFU) in spleen of murine tuberculosis models, and distinguishes both drug-sensitive and drug-resistant Mtb H37Rv strains. Mtb-IN-2 affects methionine metabolism but not folate pathway directly.
Related Catalog
References

[1]. Nawrot DE, et al. Antimycobacterial pyridine carboxamides: From design to in vivo activity. Eur J Med Chem. 2023 Oct 5;258:115617.  

 Chemical & Physical Properties

Molecular Formula C17H12N2O4
Molecular Weight 308.29
InChIKey WOVBYNARRLCBNS-UHFFFAOYSA-N
SMILES O=C(Nc1ccc(C(=O)O)c(O)c1)c1ccc2ccccc2n1
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