2181816-92-0

2181816-92-0 structure

Name: Nevadistinel
Chemical Name: Nevadistinel
CAS Number: 2181816-92-0
Molecular Formula: C₁₅H₁₈N₂O₃
Molecular Weight: 274.32
Catalog: Signaling Pathways Membrane Transporter/Ion Channel iGluR
Create Date: 2023-11-18 00:35:33
Modify Date: 2025-08-27 11:57:03
Nevadistinel (NYX-458; NYX-3054) is a positive allosteric modulator of N-methyl-D-aspartate (NMDA) receptor. Nevadistinel can be used to inhibit cognitive impairment associated with neurodegenerative diseases, such as mild cognitive impairment, mild Alzheimer's disease, Parkinson's disease, Lewy body disease[1].

Name	Nevadistinel

Description	Nevadistinel (NYX-458; NYX-3054) is a positive allosteric modulator of N-methyl-D-aspartate (NMDA) receptor. Nevadistinel can be used to inhibit cognitive impairment associated with neurodegenerative diseases, such as mild cognitive impairment, mild Alzheimer's disease, Parkinson's disease, Lewy body disease[1].
Related Catalog	Signaling Pathways >> Neuronal Signaling >> iGluR Research Areas >> Neurological Disease Signaling Pathways >> Membrane Transporter/Ion Channel >> iGluR
Target	NMDA receptor[1]
References	[1]. Khan, et al. Preparation of spiro-lactam as NMDA receptor modulators for the treatment of depression and related disorders. World Intellectual Property Organization, WO2018026798 A1. 2018-02-08.

Molecular Formula	C₁₅H₁₈N₂O₃
Molecular Weight	274.32