2892571-47-8

2892571-47-8 structure
2892571-47-8 structure
  • Name: P-gp inhibitor 14
  • Chemical Name: P-gp inhibitor 14
  • CAS Number: 2892571-47-8
  • Molecular Formula: C37H38N2O8
  • Molecular Weight: 638.71
  • Catalog: Signaling Pathways Membrane Transporter/Ion Channel P-glycoprotein
  • Create Date: 2023-09-23 10:13:01
  • Modify Date: 2024-01-04 18:40:54
  • P-gp inhibitor 14 (Compound 8a) is a high affinity P-gp inhibitor. P-gp inhibitor 14 reverses P-gp-mediated multidrug resistance (EC50=48.74 nM). P-gp inhibitor 14 has a weak inhibitory effect on CYP3A4 activity[1].

Name P-gp inhibitor 14
Description P-gp inhibitor 14 (Compound 8a) is a high affinity P-gp inhibitor. P-gp inhibitor 14 reverses P-gp-mediated multidrug resistance (EC50=48.74 nM). P-gp inhibitor 14 has a weak inhibitory effect on CYP3A4 activity[1].
Related Catalog
References

[1]. Jiang C, et al. Design and evaluation of dibenzoazepine-tetrahydroisoquinoline hybrids as potential P-glycoprotein inhibitors against multidrug resistant K562/A02 cells. Eur J Med Chem. 2023 Mar 5;249:115150.  

Molecular Formula C37H38N2O8
Molecular Weight 638.71
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