2928606-67-9

2928606-67-9 structure

Name: Pim-1 kinase inhibitor 5
Chemical Name: Pim-1 kinase inhibitor 5
CAS Number: 2928606-67-9
Molecular Formula: C₂₂H₁₃Cl₂N₃O
Molecular Weight: 406.26
Catalog: Signaling Pathways JAK/STAT Signaling Pim
Create Date: 2023-09-29 01:22:53
Modify Date: 2024-01-16 18:55:30
Pim-1 kinase inhibitor 5 (Compound 4c) is a Pim-1 kinase inhibitor (IC50: 0.61 μM). Pim-1 kinase inhibitor 5 shows cytotoxicity against cancer cells, with IC50s of 6.95-20.19 μM for HepG2, MCF-7, PC3, and HCT-116 cells[1].

Name	Pim-1 kinase inhibitor 5

Description	Pim-1 kinase inhibitor 5 (Compound 4c) is a Pim-1 kinase inhibitor (IC50: 0.61 μM). Pim-1 kinase inhibitor 5 shows cytotoxicity against cancer cells, with IC50s of 6.95-20.19 μM for HepG2, MCF-7, PC3, and HCT-116 cells[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> JAK/STAT Signaling >> Pim
References	[1]. Mansour B, et al. Cyanopyridinone- and Cyanopyridine-Based Cancer Cell Pim-1 Inhibitors: Design, Synthesis, Radiolabeling, Biodistribution, and Molecular Modeling Simulation. ACS Omega. 2023 May 24;8(22):19351-19366.

Molecular Formula	C₂₂H₁₃Cl₂N₃O
Molecular Weight	406.26