Pim-1 kinase inhibitor 5

Modify Date: 2025-08-24 07:46:04

Pim-1 kinase inhibitor 5 Structure
Pim-1 kinase inhibitor 5 structure
Common Name Pim-1 kinase inhibitor 5
CAS Number 2928606-67-9 Molecular Weight 406.26
Density N/A Boiling Point N/A
Molecular Formula C22H13Cl2N3O Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Pim-1 kinase inhibitor 5


Pim-1 kinase inhibitor 5 (Compound 4c) is a Pim-1 kinase inhibitor (IC50: 0.61 μM). Pim-1 kinase inhibitor 5 shows cytotoxicity against cancer cells, with IC50s of 6.95-20.19 μM for HepG2, MCF-7, PC3, and HCT-116 cells[1].

 Names

Name Pim-1 kinase inhibitor 5

 Pim-1 kinase inhibitor 5 Biological Activity

Description Pim-1 kinase inhibitor 5 (Compound 4c) is a Pim-1 kinase inhibitor (IC50: 0.61 μM). Pim-1 kinase inhibitor 5 shows cytotoxicity against cancer cells, with IC50s of 6.95-20.19 μM for HepG2, MCF-7, PC3, and HCT-116 cells[1].
Related Catalog
References

[1]. Mansour B, et al. Cyanopyridinone- and Cyanopyridine-Based Cancer Cell Pim-1 Inhibitors: Design, Synthesis, Radiolabeling, Biodistribution, and Molecular Modeling Simulation. ACS Omega. 2023 May 24;8(22):19351-19366.  

 Chemical & Physical Properties

Molecular Formula C22H13Cl2N3O
Molecular Weight 406.26
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