2378257-72-6

2378257-72-6 structure

Name: PROTAC KRAS G12C degrader-2
Chemical Name: PROTAC KRAS G12C degrader-2
CAS Number: 2378257-72-6
Molecular Formula: C₅₁H₅₃ClFN₉O₇
Molecular Weight: 958.47
Catalog: Signaling Pathways GPCR/G Protein Ras
Create Date: 2023-09-20 09:51:31
Modify Date: 2024-01-09 21:48:34
PROTAC KRAS G12C degrader-2 (compound 432) is a modulator of K-Ras protein hydrolysis. PROTAC KRAS G12C degrader-2 is a bifunctional compound, which contain on one end a cereblon inhibitor of apoptosis proteins (IAP) and on the other end a moiety which binds KRAS[1].

Name	PROTAC KRAS G12C degrader-2

Description	PROTAC KRAS G12C degrader-2 (compound 432) is a modulator of K-Ras protein hydrolysis. PROTAC KRAS G12C degrader-2 is a bifunctional compound, which contain on one end a cereblon inhibitor of apoptosis proteins (IAP) and on the other end a moiety which binds KRAS[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> GPCR/G Protein >> Ras Signaling Pathways >> PROTAC >> PROTAC
References	[1]. Crew Andrew, et al. Preparation of bifunctional compounds as modulators of proteolysis useful for treating cancer. World Intellectual Property Organization, WO2019195609 A2. 2019-10-10.

Molecular Formula	C₅₁H₅₃ClFN₉O₇
Molecular Weight	958.47