PROTAC KRAS G12C degrader-2

Modify Date: 2024-01-09 21:48:34

PROTAC KRAS G12C degrader-2 structure	Common Name	PROTAC KRAS G12C degrader-2
	CAS Number	2378257-72-6	Molecular Weight	958.47
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₅₁H₅₃ClFN₉O₇	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of PROTAC KRAS G12C degrader-2

PROTAC KRAS G12C degrader-2 (compound 432) is a modulator of K-Ras protein hydrolysis. PROTAC KRAS G12C degrader-2 is a bifunctional compound, which contain on one end a cereblon inhibitor of apoptosis proteins (IAP) and on the other end a moiety which binds KRAS[1].

Name	PROTAC KRAS G12C degrader-2

Description	PROTAC KRAS G12C degrader-2 (compound 432) is a modulator of K-Ras protein hydrolysis. PROTAC KRAS G12C degrader-2 is a bifunctional compound, which contain on one end a cereblon inhibitor of apoptosis proteins (IAP) and on the other end a moiety which binds KRAS[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> GPCR/G Protein >> Ras Signaling Pathways >> PROTAC >> PROTAC
References	[1]. Crew Andrew, et al. Preparation of bifunctional compounds as modulators of proteolysis useful for treating cancer. World Intellectual Property Organization, WO2019195609 A2. 2019-10-10.

Molecular Formula	C₅₁H₅₃ClFN₉O₇
Molecular Weight	958.47

PROTAC KRAS G12C degrader-2

Use of PROTAC KRAS G12C degrader-2

Names

PROTAC KRAS G12C degrader-2 Biological Activity

Chemical & Physical Properties