PROTAC KRAS G12C degrader-2

Modify Date: 2024-01-09 21:48:34

PROTAC KRAS G12C degrader-2 Structure
PROTAC KRAS G12C degrader-2 structure
Common Name PROTAC KRAS G12C degrader-2
CAS Number 2378257-72-6 Molecular Weight 958.47
Density N/A Boiling Point N/A
Molecular Formula C51H53ClFN9O7 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of PROTAC KRAS G12C degrader-2


PROTAC KRAS G12C degrader-2 (compound 432) is a modulator of K-Ras protein hydrolysis. PROTAC KRAS G12C degrader-2 is a bifunctional compound, which contain on one end a cereblon inhibitor of apoptosis proteins (IAP) and on the other end a moiety which binds KRAS[1].

 Names

Name PROTAC KRAS G12C degrader-2

 PROTAC KRAS G12C degrader-2 Biological Activity

Description PROTAC KRAS G12C degrader-2 (compound 432) is a modulator of K-Ras protein hydrolysis. PROTAC KRAS G12C degrader-2 is a bifunctional compound, which contain on one end a cereblon inhibitor of apoptosis proteins (IAP) and on the other end a moiety which binds KRAS[1].
Related Catalog
References

[1]. Crew Andrew, et al. Preparation of bifunctional compounds as modulators of proteolysis useful for treating cancer. World Intellectual Property Organization, WO2019195609 A2. 2019-10-10.

 Chemical & Physical Properties

Molecular Formula C51H53ClFN9O7
Molecular Weight 958.47
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