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2278205-04-0

2278205-04-0 structure

2278205-04-0 structure

Name: Protein kinase inhibitor 4
Chemical Name: Protein kinase inhibitor 4
CAS Number: 2278205-04-0
Molecular Formula: C₂₅H₂₄F₂N₆O₃S
Molecular Weight: 526.56
Catalog: Signaling Pathways Protein Tyrosine Kinase/RTK ROS
Create Date: 2023-09-20 18:37:19
Modify Date: 2024-01-22 19:11:50
Protein kinase inhibitor 4 (Compound 3) is a protein kinase inhibitor that inhibits TRK-A and ROS1 (IC50=3.0 nM and 104 nM respectively)[1].

Name	Protein kinase inhibitor 4

Description	Protein kinase inhibitor 4 (Compound 3) is a protein kinase inhibitor that inhibits TRK-A and ROS1 (IC50=3.0 nM and 104 nM respectively)[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Protein Tyrosine Kinase/RTK >> ROS Signaling Pathways >> Protein Tyrosine Kinase/RTK >> Trk Receptor
Target	IC50: 3.0 nM (Trk-A), 104 nM (ROS-1)[1]
References	[1]. Dawei Zhang, et al. Substituted pyrazolopyrimidines useful as kinases inhibitors. Patent. WO2019029629A1.

Molecular Formula	C₂₅H₂₄F₂N₆O₃S
Molecular Weight	526.56

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