335394-78-0

335394-78-0 structure
335394-78-0 structure
  • Name: PU-48
  • Chemical Name: PU-48
  • CAS Number: 335394-78-0
  • Molecular Formula: C14H12N2O3S
  • Molecular Weight: 288.32
  • Catalog: Research Areas Metabolic Disease
  • Create Date: 2023-09-22 21:38:13
  • Modify Date: 2025-09-08 11:37:10
  • PU-48 is a potent urea transporters A (UT-A) inhibitor (IC50=0.32 μM). PU-48 has a good diuretic effect in mouse models, and shows little or no cytotoxicity. PU-48 has the potential to be developed as a diuretic[1].

Name PU-48
Description PU-48 is a potent urea transporters A (UT-A) inhibitor (IC50=0.32 μM). PU-48 has a good diuretic effect in mouse models, and shows little or no cytotoxicity. PU-48 has the potential to be developed as a diuretic[1].
Related Catalog
References

[1]. Ren H, et al. Thienoquinolins exert diuresis by strongly inhibiting UT-A urea transporters. Am J Physiol Renal Physiol. 2014 Dec 15;307(12):F1363-72.  

Molecular Formula C14H12N2O3S
Molecular Weight 288.32
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