2244807-49-4

2244807-49-4 structure

Name: URAT1 inhibitor 6
Chemical Name: URAT1 inhibitor 6
CAS Number: 2244807-49-4
Molecular Formula: C₉H₇BrN₃NaO₂S₂
Molecular Weight: 356.19
Catalog: Signaling Pathways Membrane Transporter/Ion Channel URAT1
Create Date: 2023-09-20 11:32:27
Modify Date: 2024-04-09 09:53:35
URAT1 inhibitor 6 (Compound 1h) is a potent URAT1 inhibitor (IC50: 35 nM for hURAT1). URAT1 inhibitor 6 is 200- and 8-fold more potent than parent Lesinurad (HY-15258) and Benzbromarone (HY-B1135). URAT1 inhibitor 6 can be used for research of inflammation[1].

Name	URAT1 inhibitor 6

Description	URAT1 inhibitor 6 (Compound 1h) is a potent URAT1 inhibitor (IC50: 35 nM for hURAT1). URAT1 inhibitor 6 is 200- and 8-fold more potent than parent Lesinurad (HY-15258) and Benzbromarone (HY-B1135). URAT1 inhibitor 6 can be used for research of inflammation[1].
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> URAT1 Research Areas >> Inflammation/Immunology
References	[1]. Cai W, et al. Systematic Structure-Activity Relationship (SAR) Exploration of Diarylmethane Backbone and Discovery of A Highly Potent Novel Uric Acid Transporter 1 (URAT1) Inhibitor. Molecules. 2018 Jan 27;23(2):252.

Molecular Formula	C₉H₇BrN₃NaO₂S₂
Molecular Weight	356.19