1632002-28-8

1632002-28-8 structure

Name: URAT1 inhibitor 7
Chemical Name: URAT1 inhibitor 7
CAS Number: 1632002-28-8
Molecular Formula: C₁₉H₁₀ClFN₄O₃S
Molecular Weight: 428.82
Catalog: Signaling Pathways Membrane Transporter/Ion Channel URAT1
Create Date: 2023-09-23 18:41:03
Modify Date: 2024-01-04 18:01:46
URAT1 inhibitor 7 (compound 10f) is a potent URAT1 inhibitor, with an IC50 of 12 nM. URAT1 inhibitor 7 exhibits microsomal stability (HLM <13 µL/min/mg). URAT1 inhibitor 7 also inhibits CYP2C9, with an IC50 of 4.2 μM. URAT1 inhibitor 7 can be used for gout research[1].

Name	URAT1 inhibitor 7

Description	URAT1 inhibitor 7 (compound 10f) is a potent URAT1 inhibitor, with an IC50 of 12 nM. URAT1 inhibitor 7 exhibits microsomal stability (HLM <13 µL/min/mg). URAT1 inhibitor 7 also inhibits CYP2C9, with an IC50 of 4.2 μM. URAT1 inhibitor 7 can be used for gout research[1].
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> URAT1 Research Areas >> Inflammation/Immunology
References	[1]. Storer R I, et al. The discovery and evaluation of diaryl ether heterocyclic sulfonamides as URAT1 inhibitors for the treatment of gout. MedChemComm, 2016:10.1039.C6MD00190D.

Molecular Formula	C₁₉H₁₀ClFN₄O₃S
Molecular Weight	428.82