1115910-36-5

1115910-36-5 structure

Name: icFSP1
Chemical Name: icFSP1
CAS Number: 1115910-36-5
Molecular Formula: C₂₆H₂₅N₃O₅
Molecular Weight: 459.5
Catalog: Signaling Pathways Apoptosis Ferroptosis
Create Date: 2023-10-20 13:54:55
Modify Date: 2026-08-06 17:55:21
icFSP1 is a potent ferroptosis suppressor protein-1 (FSP1) inhibitor. icFSP1 does not competitively inhibit FSP1 enzyme activity, but instead triggers subcellular relocalization of FSP1 from the membrane and FSP1 condensation before ferroptosis induction, in synergism with GPX4 inhibition[1].

Name	icFSP1

Description	icFSP1 is a potent ferroptosis suppressor protein-1 (FSP1) inhibitor. icFSP1 does not competitively inhibit FSP1 enzyme activity, but instead triggers subcellular relocalization of FSP1 from the membrane and FSP1 condensation before ferroptosis induction, in synergism with GPX4 inhibition[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Apoptosis >> Ferroptosis
References	[1]. Toshitaka Nakamura, et al. Phase separation of FSP1 promotes ferroptosis. Nature. 2023 Jul;619(7969):371-377.