19179-12-5

19179-12-5 structure

Name: Cyclo(Pro-Gly)
Chemical Name: 2,3,6,7,8,8a-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione
CAS Number: 19179-12-5
Molecular Formula: C₇H₁₀N₂O₂
Molecular Weight: 154.167
Catalog: Research Areas Neurological Disease
Create Date: 2018-10-19 11:51:15
Modify Date: 2025-08-22 00:19:10
Cyclo-(Pro-Gly) (Pyrrolopiperazine-2,5-dione), an alkaloid isolated from green algae Ulva prolifera, possesses antialgal activity against the common harmful red tide microalgae[1]. Cyclo-(Pro-Gly) (Pyrrolopiperazine-2,5-dione) possesses antiamnesic effects and neuroprotective actions[2].

Name	2,3,6,7,8,8a-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione
Synonyms	Cyclo-Gly-Pro cyclo-Glycyl-L-Proline DL-2,5-Dioxo-1,4-diazabicyclo<4.3.0>nonane Hexahydropyrrolo[1,2-a]pyrazine-1,4-dione Gly-Pro-diketopiperazine Glycyl-L-proline lactam cyclo-GP cyclo-L-prolylglycine Pyrrolo[1,2-a]pyrazine-1,4-dione, hexahydro-

Description	Cyclo-(Pro-Gly) (Pyrrolopiperazine-2,5-dione), an alkaloid isolated from green algae Ulva prolifera, possesses antialgal activity against the common harmful red tide microalgae[1]. Cyclo-(Pro-Gly) (Pyrrolopiperazine-2,5-dione) possesses antiamnesic effects and neuroprotective actions[2].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Neurological Disease
In Vivo	Cyclo-(Pro-Gly) (0.1 and 10 mg/kg, ip ) seems to be a memory facilitating substance and its presence in rat brain suggests the existence of a new mechanism of memory regulation[3].
References	[1]. Ying-ying Sun, et al. Isolation, Purification, and Identification of Antialgal Substances in Green Alga Ulva Prolifera for Antialgal Activity Against the Common Harmful Red Tide Microalgae. Environ Sci Pollut Res Int. 2016 Jan;23(2):1449-59. [2]. Fumitaka Hayasaka, et al. Production Method for Cyclic Dipeptide Derived from Native Collagen. Food Science and Technology Research, 22 (4), 477-483, 2016. [3]. T A Gudasheva, et al. Identification of a Novel Endogenous Memory Facilitating Cyclic Dipeptide Cyclo-Prolylglycine in Rat Brain. FEBS Lett. 1996 Aug 5;391(1-2):149-52.

HS Code	2933990090

Precursor 0
DownStream 3
5654-83-1 56-40-6 147-85-3

HS Code	2933990090
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%