Cyclo(Pro-Gly)

Modify Date: 2024-01-06 00:33:12

Cyclo(Pro-Gly) Structure
Cyclo(Pro-Gly) structure
Common Name Cyclo(Pro-Gly)
CAS Number 19179-12-5 Molecular Weight 154.167
Density 1.3±0.1 g/cm3 Boiling Point 447.9±34.0 °C at 760 mmHg
Molecular Formula C7H10N2O2 Melting Point N/A
MSDS N/A Flash Point 224.7±25.7 °C

 Use of Cyclo(Pro-Gly)


Cyclo-(Pro-Gly) (Pyrrolopiperazine-2,5-dione), an alkaloid isolated from green algae Ulva prolifera, possesses antialgal activity against the common harmful red tide microalgae[1]. Cyclo-(Pro-Gly) (Pyrrolopiperazine-2,5-dione) possesses antiamnesic effects and neuroprotective actions[2].

 Names

Name 2,3,6,7,8,8a-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione
Synonym More Synonyms

 Cyclo(Pro-Gly) Biological Activity

Description Cyclo-(Pro-Gly) (Pyrrolopiperazine-2,5-dione), an alkaloid isolated from green algae Ulva prolifera, possesses antialgal activity against the common harmful red tide microalgae[1]. Cyclo-(Pro-Gly) (Pyrrolopiperazine-2,5-dione) possesses antiamnesic effects and neuroprotective actions[2].
Related Catalog
In Vivo Cyclo-(Pro-Gly) (0.1 and 10 mg/kg, ip ) seems to be a memory facilitating substance and its presence in rat brain suggests the existence of a new mechanism of memory regulation[3].
References

[1]. Ying-ying Sun, et al. Isolation, Purification, and Identification of Antialgal Substances in Green Alga Ulva Prolifera for Antialgal Activity Against the Common Harmful Red Tide Microalgae. Environ Sci Pollut Res Int. 2016 Jan;23(2):1449-59.

[2]. Fumitaka Hayasaka, et al. Production Method for Cyclic Dipeptide Derived from Native Collagen. Food Science and Technology Research, 22 (4), 477-483, 2016.

[3]. T A Gudasheva, et al. Identification of a Novel Endogenous Memory Facilitating Cyclic Dipeptide Cyclo-Prolylglycine in Rat Brain. FEBS Lett. 1996 Aug 5;391(1-2):149-52.

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 447.9±34.0 °C at 760 mmHg
Molecular Formula C7H10N2O2
Molecular Weight 154.167
Flash Point 224.7±25.7 °C
Exact Mass 154.074234
PSA 52.90000
LogP -2.74
Vapour Pressure 0.0±1.1 mmHg at 25°C
Index of Refraction 1.569

 Safety Information

HS Code 2933990090

 Precursor & DownStream

Precursor  0

DownStream  3

 Customs

HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

Cyclo-Gly-Pro
cyclo-Glycyl-L-Proline
DL-2,5-Dioxo-1,4-diazabicyclo<4.3.0>nonane
Hexahydropyrrolo[1,2-a]pyrazine-1,4-dione
Gly-Pro-diketopiperazine
Glycyl-L-proline lactam
cyclo-GP
cyclo-L-prolylglycine
Pyrrolo[1,2-a]pyrazine-1,4-dione, hexahydro-
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