491611-43-9

491611-43-9 structure

Name: MRS2298
Chemical Name: MRS2298
CAS Number: 491611-43-9
Molecular Formula: C₁₀H₁₆ClN₅O₈P₂
Molecular Weight: 431.66
Catalog: Signaling Pathways GPCR/G Protein P2Y Receptor
Create Date: 2023-11-24 19:41:12
Modify Date: 2024-01-28 22:26:02
MRS2298? is a potent acyclic P2Y1 receptor antagonist with a Ki of 29.6 nM. MRS2298 inhibits the ADP-induced aggregation of human platelets with an IC50 of 62.8 nM. MRS2298 inhibits Ca2+ rise in platelets with an IC50 of 810 nM[1].

Name	MRS2298
Synonyms	MRS 2298 MRS-2298

Description	MRS2298? is a potent acyclic P2Y1 receptor antagonist with a Ki of 29.6 nM. MRS2298 inhibits the ADP-induced aggregation of human platelets with an IC50 of 62.8 nM. MRS2298 inhibits Ca2+ rise in platelets with an IC50 of 810 nM[1].
Related Catalog	Research Areas >> Cardiovascular Disease Signaling Pathways >> GPCR/G Protein >> P2Y Receptor
References	[1]. Marco Cattaneo, et al. Antiaggregatory activity in human platelets of potent antagonists of the P2Y 1 receptor. Biochem Pharmacol. 2004 Nov 15;68(10):1995-2002.