202979-51-9

202979-51-9 structure

Name: 3,4-Piperidinediol, 5-(hydroxymethyl)-, (3R,4R,5S)- (9CI)
Chemical Name: (3R,4R,5S)-5-(hydroxymethyl)piperidine-3,4-diol
CAS Number: 202979-51-9
Molecular Formula: C₆H₁₃NO₃
Molecular Weight: 147.17200
Catalog: Research Areas Metabolic Disease
Create Date: 2016-04-06 22:32:09
Modify Date: 2026-08-02 18:00:49
L-Afegostat (5-epi-Isofagomine) is a glycosidase inhibitor. L-Afegostat is an iminosugar that can be used for the synthesis of carbohydrates. L-Afegostat shows enzyme inhibition to β-Glucosidase with an Ki of 30 μM[1].

Name	(3R,4R,5S)-5-(hydroxymethyl)piperidine-3,4-diol
Synonyms	(3R,4R,5S) 5-epi-Isofagomine (3R,4R,5S)-5-(hydroxymethyl)-3,4-Piperidinediol L-Afegostat [3R-(3.alpha.,4.beta.,5.beta.)]-5-(hydroxymethyl)-3,4-Piperidinediol 3,4-Piperidinediol, 5-(hydroxymethyl)-, (3R,4R,5S)

Description	L-Afegostat (5-epi-Isofagomine) is a glycosidase inhibitor. L-Afegostat is an iminosugar that can be used for the synthesis of carbohydrates. L-Afegostat shows enzyme inhibition to β-Glucosidase with an Ki of 30 μM[1].
Related Catalog	Research Areas >> Metabolic Disease
References	[1]. Pandey G, et al. A new access to polyhydroxy piperidines of the azasugar class: synthesis and glycosidase inhibition studies. Org Biomol Chem. 2003 Oct 7;1(19):3321-6.