915729-95-2

915729-95-2 structure
915729-95-2 structure

Name BMS-767778
Description BMS-767778, a DPP-4 inhibitor, is used potentially for the treatment of type 2 diabetes.
References 1. Devasthale P, Wang Y, Wang W, Fevig J, Feng J, Wang A, Harrity T, Egan D, Morgan N, Cap M, Fura A, Klei HE, Kish K, Weigelt C, Sun L, Levesque P, Moulin F, Li YX, Zahler R, Kirby MS, Hamann LG. Optimization of activity, selectivity, and liability profiles in 5-oxopyrrolopyridine DPP4 inhibitors leading to clinical candidate (Sa)-2-(3-(aminomethyl)-4-(2,4-dichlorophenyl)-2-methyl-5-oxo-5H-pyrrolo[3,4-b]py ridin-6(7H)-yl)-N,N-dimethylacetamide (BMS-767778). J Med Chem. 2013 Sep 26;56(18):7343-57. doi: 10.1021/jm4008906. PubMed PMID: 23964740.
Molecular Formula C19H20Cl2N4O2
Molecular Weight 407.29