Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Palmitic acid
Price: Check
Purity: 98.0%
Stocking Period: 10 Day
Contact: Yang
Email: sales@echemcloud.com

2196186-84-0

2196186-84-0 structure

2196186-84-0 structure

Name: APG-2449
Chemical Name: APG-2449
CAS Number: 2196186-84-0
Molecular Formula: C₃₃H₄₂ClN₅O₄S
Molecular Weight: 640.24
Catalog: Signaling Pathways Protein Tyrosine Kinase/RTK ALK
Create Date: 2023-12-09 12:02:55
Modify Date: 2024-01-02 18:56:20
APG-2449 is an orally active ALK/ROS1/FAK inhibitor. APG-2449 shows antitumor activity in mouse models of non-small cell lung cancer (NSCLC)[1].

Name	APG-2449

Description	APG-2449 is an orally active ALK/ROS1/FAK inhibitor. APG-2449 shows antitumor activity in mouse models of non-small cell lung cancer (NSCLC)[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Protein Tyrosine Kinase/RTK >> ROS Signaling Pathways >> Protein Tyrosine Kinase/RTK >> ALK Signaling Pathways >> Protein Tyrosine Kinase/RTK >> FAK
References	[1]. Fang DD, et al. Discovery of a novel ALK/ROS1/FAK inhibitor, APG-2449, in preclinical non-small cell lung cancer and ovarian cancer models. BMC Cancer. 2022 Jul 11;22(1):752.

Molecular Formula	C₃₃H₄₂ClN₅O₄S
Molecular Weight	640.24

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.