2944452-34-8

2944452-34-8 structure
2944452-34-8 structure
  • Name: EGFR-IN-88
  • Chemical Name: EGFR-IN-88
  • CAS Number: 2944452-34-8
  • Molecular Formula: C22H18Cl2N4O2S
  • Molecular Weight: 473.37
  • Catalog: Signaling Pathways Apoptosis Apoptosis
  • Create Date: 2024-04-08 16:30:23
  • Modify Date: 2024-04-08 16:30:23
  • EGFR-IN-88 (Compound 4i) is an EGFR inhibitor (IC50: 87 nM). EGFR-IN-88 shows cytotoxicity against A549 cell with an IC50? of 3.902? μM. EGFR-IN-88 can induce cell apoptosis[1].

Name EGFR-IN-88
Description EGFR-IN-88 (Compound 4i) is an EGFR inhibitor (IC50: 87 nM). EGFR-IN-88 shows cytotoxicity against A549 cell with an IC50? of 3.902? μM. EGFR-IN-88 can induce cell apoptosis[1].
Related Catalog
Target

87 nM (EGFR)[1]

References

[1]. Ali SH, et al. Design, synthesis, and molecular docking studies of novel quinoxaline derivatives as anticancer agents. Chem Biol Drug Des. 2023 Aug;102(2):303-315.  

Molecular Formula C22H18Cl2N4O2S
Molecular Weight 473.37
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