2584947-79-3

2584947-79-3 structure

Name: PXS-6302 hydrochloride
Chemical Name: PXS-6302 hydrochloride
CAS Number: 2584947-79-3
Molecular Formula: C₁₀H₁₁ClF₃NO₂S
Molecular Weight: 301.71
Catalog: Signaling Pathways Neuronal Signaling Monoamine Oxidase
Create Date: 2023-11-05 16:24:48
Modify Date: 2024-01-10 08:52:12
PXS-6302 hydrochloride is an irreversible lysyl oxidase inhibitor with IC50s of 3.7 μM (Bovine LOX), 3.4 μM (rh LOXL1), 0.4 μM (rh LOXL2), 1.5 μM (rh LOXL3), 0.3 μM (rh LOXL4), respectively. PXS-6302 hydrochloride has readily skin penetrability, reduces collagen deposition and significantly improves scar appearance[1].

Name	PXS-6302 hydrochloride

Description	PXS-6302 hydrochloride is an irreversible lysyl oxidase inhibitor with IC50s of 3.7 μM (Bovine LOX), 3.4 μM (rh LOXL1), 0.4 μM (rh LOXL2), 1.5 μM (rh LOXL3), 0.3 μM (rh LOXL4), respectively. PXS-6302 hydrochloride has readily skin penetrability, reduces collagen deposition and significantly improves scar appearance[1].
Related Catalog	Signaling Pathways >> Neuronal Signaling >> Monoamine Oxidase Research Areas >> Inflammation/Immunology
References	[1]. Chaudhari N, et al. Topical application of an irreversible small molecule inhibitor of lysyl oxidases ameliorates skin scarring and fibrosis. Nat Commun. 2022 Sep 22;13(1):5555.

Molecular Formula	C₁₀H₁₁ClF₃NO₂S
Molecular Weight	301.71