2473270-96-9
2473270-96-9 structure
- Name: Thalidomide-O-amido-C11-COOH
- Chemical Name: Thalidomide-O-amido-C11-COOH
- CAS Number: 2473270-96-9
- Molecular Formula: C27H35N3O8
- Molecular Weight: 529.58
- Catalog: Signaling Pathways Antibody-drug Conjugate PROTAC-linker Conjugate for PAC
- Create Date: 2023-11-26 13:51:08
- Modify Date: 2025-10-09 11:47:09
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Thalidomide-O-amido-C11-COOH (compound IMiD acid 1) is an E3 ligase ligand and linker CRBN (Cereblon) conjugate. Thalidomide-O-amido-C11-COOH can be used to synthesize PROTAC that target the degradation of DOT1L[1].
| Name | Thalidomide-O-amido-C11-COOH |
|---|
| Description | Thalidomide-O-amido-C11-COOH (compound IMiD acid 1) is an E3 ligase ligand and linker CRBN (Cereblon) conjugate. Thalidomide-O-amido-C11-COOH can be used to synthesize PROTAC that target the degradation of DOT1L[1]. |
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| Related Catalog | |
| References |
[1]. Jun Qi, et al. Small molecules for dot1l degradation and uses thereof. Patent WO2023069348A1. |
| Molecular Formula | C27H35N3O8 |
|---|---|
| Molecular Weight | 529.58 |