Thalidomide-O-amido-C11-COOH

Modify Date: 2025-10-09 11:47:09

Thalidomide-O-amido-C11-COOH structure	Common Name	Thalidomide-O-amido-C11-COOH
	CAS Number	2473270-96-9	Molecular Weight	529.58
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₇H₃₅N₃O₈	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Thalidomide-O-amido-C11-COOH

Thalidomide-O-amido-C11-COOH (compound IMiD acid 1) is an E3 ligase ligand and linker CRBN (Cereblon) conjugate. Thalidomide-O-amido-C11-COOH can be used to synthesize PROTAC that target the degradation of DOT1L[1].

Name	Thalidomide-O-amido-C11-COOH

Description	Thalidomide-O-amido-C11-COOH (compound IMiD acid 1) is an E3 ligase ligand and linker CRBN (Cereblon) conjugate. Thalidomide-O-amido-C11-COOH can be used to synthesize PROTAC that target the degradation of DOT1L[1].
Related Catalog	Signaling Pathways >> PROTAC >> PROTAC-linker Conjugate for PAC Research Areas >> Cancer Signaling Pathways >> Antibody-drug Conjugate >> PROTAC-linker Conjugate for PAC
References	[1]. Jun Qi, et al. Small molecules for dot1l degradation and uses thereof. Patent WO2023069348A1.

Molecular Formula	C₂₇H₃₅N₃O₈
Molecular Weight	529.58

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