2403729-27-9

2403729-27-9 structure

Name: Topoisomerase II inhibitor 16
Chemical Name: Topoisomerase II inhibitor 16
CAS Number: 2403729-27-9
Molecular Formula: C₁₉H₁₂F₄N₆O
Molecular Weight: 416.33
Catalog: Signaling Pathways Cell Cycle/DNA Damage Topoisomerase
Create Date: 2024-01-08 21:42:37
Modify Date: 2024-01-08 21:42:37
Topoisomerase II inhibitor 16 (compound CT3) is a selective, orally active, brain-penetrant and irreversible trypanosomal topoisomerase II inhibitor by stabilizing double-stranded DNA:enzyme cleavage complexes. Topoisomerase II inhibitor 16 has the potential for Chagas disease research[1].

Name	Topoisomerase II inhibitor 16

Description	Topoisomerase II inhibitor 16 (compound CT3) is a selective, orally active, brain-penetrant and irreversible trypanosomal topoisomerase II inhibitor by stabilizing double-stranded DNA:enzyme cleavage complexes. Topoisomerase II inhibitor 16 has the potential for Chagas disease research[1].
Related Catalog	Signaling Pathways >> Cell Cycle/DNA Damage >> Topoisomerase Research Areas >> Infection
References	[1]. Srinivasa P S Rao, et al. Cyanotriazoles are selective topoisomerase II poisons that rapidly cure trypanosome infections. Science. 2023 Jun 30;380(6652):1349-1356.

Molecular Formula	C₁₉H₁₂F₄N₆O
Molecular Weight	416.33