Topoisomerase II inhibitor 16

Modify Date: 2025-11-29 11:12:01

Topoisomerase II inhibitor 16 Structure
Topoisomerase II inhibitor 16 structure
 Common Name Topoisomerase II inhibitor 16
CAS Number 2403729-27-9 Molecular Weight 416.33
Density N/A Boiling Point N/A
Molecular Formula C19H12F4N6O Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Topoisomerase II inhibitor 16


Topoisomerase II inhibitor 16 (compound CT3) is a selective, orally active, brain-penetrant and irreversible trypanosomal topoisomerase II inhibitor by stabilizing double-stranded DNA:enzyme cleavage complexes. Topoisomerase II inhibitor 16 has the potential for Chagas disease research[1].

 Names

Name Topoisomerase II inhibitor 16

 Topoisomerase II inhibitor 16 Biological Activity

Description Topoisomerase II inhibitor 16 (compound CT3) is a selective, orally active, brain-penetrant and irreversible trypanosomal topoisomerase II inhibitor by stabilizing double-stranded DNA:enzyme cleavage complexes. Topoisomerase II inhibitor 16 has the potential for Chagas disease research[1].
Related Catalog
References

[1]. Srinivasa P S Rao, et al. Cyanotriazoles are selective topoisomerase II poisons that rapidly cure trypanosome infections. Science. 2023 Jun 30;380(6652):1349-1356.

 Chemical & Physical Properties

Molecular Formula C19H12F4N6O
Molecular Weight 416.33
InChIKey JDTWUDDOSHJEIZ-UHFFFAOYSA-N
SMILES N#Cc1ncn(CC(=O)N2Cc3ccc(-c4cc(F)cnc4C(F)(F)F)cc3C2)n1
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Chemsrc provides Topoisomerase II inhibitor 16(CAS#:2403729-27-9) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of Topoisomerase II inhibitor 16 are included as well.>> amp version: Topoisomerase II inhibitor 16

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