171745-13-4
171745-13-4 structure
- Name: 4-(3-bromoanilino)-6,7-diethoxyquinazoline
- Chemical Name: N-(3-bromophenyl)-6,7-diethoxyquinazolin-4-amine
- CAS Number: 171745-13-4
- Molecular Formula: C18H18BrN3O2
- Molecular Weight: 388.26
- Catalog: Signaling Pathways JAK/STAT Signaling EGFR
- Create Date: 2018-12-26 08:10:41
- Modify Date: 2024-01-02 19:37:14
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EGFR-IN-80 (compound 30) is an EGFR inhibitor with a pIC50 of 10.6[1].
| Name | N-(3-bromophenyl)-6,7-diethoxyquinazolin-4-amine |
|---|---|
| Synonyms |
compound 56
N-(3-Bromophenyl)-6,7-diethoxyquinazolin-4-amine 4-(3'-bromoanilino)-6,7-diethoxyquinazoline 4-(3-bromoanilino)-6,7-diethoxyquinazoline 4-quinazolinamine, N-(3-bromophenyl)-6,7-diethoxy- N-(3-Bromophenyl)-6,7-diethoxy-4-quinazolinamine 4-[(3-bromophenyl)amino]-6,7-diethoxyquinazoline (3-Bromophenyl)-(6,7-diethoxyquinazolin-4-yl)-amine YXOXHAUUTIOBDA-UHFFFAOYSA |
| Description | EGFR-IN-80 (compound 30) is an EGFR inhibitor with a pIC50 of 10.6[1]. |
|---|---|
| Related Catalog | |
| Target |
EGFR:10.6 (pIC50) |
| References |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 492.6±45.0 °C at 760 mmHg |
| Molecular Formula | C18H18BrN3O2 |
| Molecular Weight | 388.26 |
| Flash Point | 251.7±28.7 °C |
| Exact Mass | 387.058228 |
| PSA | 56.27000 |
| LogP | 5.14 |
| Vapour Pressure | 0.0±1.3 mmHg at 25°C |
| Index of Refraction | 1.652 |
|
~%
171745-13-4 |
| Literature: Bridges; Zhou; Cody; Rewcastle; McMichael; Showalter; Fry; Kraker; Denny Journal of Medicinal Chemistry, 1996 , vol. 39, # 1 p. 267 - 276 |
|
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171745-13-4 |
| Literature: Bridges; Zhou; Cody; Rewcastle; McMichael; Showalter; Fry; Kraker; Denny Journal of Medicinal Chemistry, 1996 , vol. 39, # 1 p. 267 - 276 |
|
~%
171745-13-4 |
| Literature: Bridges; Zhou; Cody; Rewcastle; McMichael; Showalter; Fry; Kraker; Denny Journal of Medicinal Chemistry, 1996 , vol. 39, # 1 p. 267 - 276 |
|
~%
171745-13-4 |
| Literature: Bridges; Zhou; Cody; Rewcastle; McMichael; Showalter; Fry; Kraker; Denny Journal of Medicinal Chemistry, 1996 , vol. 39, # 1 p. 267 - 276 |
|
~%
171745-13-4 |
| Literature: Wright, Stephen W.; Hageman, David L.; McClure, Lester D.; Carlo, Anthony A.; Treadway, Judith L.; Mathiowetz, Alan M.; Withka, Jane M.; Bauer, Paul H. Bioorganic and Medicinal Chemistry Letters, 2001 , vol. 11, # 1 p. 17 - 21 |
| Precursor 5 | |
|---|---|
| DownStream 0 | |