Shanghai Nianxing Industrial Co., Ltd
China
Product Name: 4-(3-bromoanilino)-6,7-diethoxyquinazoline
Price: Check
Purity: 98.0%
Stocking Period: 10 Day
Contact: Yang
Email: sales@echemcloud.com

DC Chemicals Limited
China
Product Name: EGFR-IN-80
Price: ￥550.0/100mg ￥850.0/250mg ￥1800.0/1g
Purity: 98.0%
Stocking Period: 10 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 4-[(3-BROMOPHENYL)AMINO]-6,7-DIETHOXYQUINAZOLINE
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

171745-13-4

171745-13-4 structure

171745-13-4 structure

Name: 4-(3-bromoanilino)-6,7-diethoxyquinazoline
Chemical Name: N-(3-bromophenyl)-6,7-diethoxyquinazolin-4-amine
CAS Number: 171745-13-4
Molecular Formula: C₁₈H₁₈BrN₃O₂
Molecular Weight: 388.26
Catalog: Signaling Pathways JAK/STAT Signaling EGFR
Create Date: 2018-12-26 08:10:41
Modify Date: 2025-08-27 09:25:21
EGFR-IN-80 (compound 30) is an EGFR inhibitor with a pIC50 of 10.6[1].

Name	N-(3-bromophenyl)-6,7-diethoxyquinazolin-4-amine
Synonyms	compound 56 N-(3-Bromophenyl)-6,7-diethoxyquinazolin-4-amine 4-(3'-bromoanilino)-6,7-diethoxyquinazoline 4-(3-bromoanilino)-6,7-diethoxyquinazoline 4-quinazolinamine, N-(3-bromophenyl)-6,7-diethoxy- N-(3-Bromophenyl)-6,7-diethoxy-4-quinazolinamine 4-[(3-bromophenyl)amino]-6,7-diethoxyquinazoline (3-Bromophenyl)-(6,7-diethoxyquinazolin-4-yl)-amine YXOXHAUUTIOBDA-UHFFFAOYSA

Description	EGFR-IN-80 (compound 30) is an EGFR inhibitor with a pIC50 of 10.6[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> JAK/STAT Signaling >> EGFR Signaling Pathways >> Protein Tyrosine Kinase/RTK >> EGFR
Target	EGFR:10.6 (pIC50)
References	[1]. Farhan Ahmad Pasha, et al. In silico QSAR studies of anilinoquinolines as EGFR inhibitors. J Mol Model. 2010 Feb;16(2):263-77.

Density	1.4±0.1 g/cm3
Boiling Point	492.6±45.0 °C at 760 mmHg
Molecular Formula	C₁₈H₁₈BrN₃O₂
Molecular Weight	388.26
Flash Point	251.7±28.7 °C
Exact Mass	387.058228
PSA	56.27000
LogP	5.14
Vapour Pressure	0.0±1.3 mmHg at 25°C
Index of Refraction	1.652

591-19-5 structure

591-19-5

~%

171745-13-4 structure

171745-13-4

Literature: Bridges; Zhou; Cody; Rewcastle; McMichael; Showalter; Fry; Kraker; Denny Journal of Medicinal Chemistry, 1996 , vol. 39, # 1 p. 267 - 276

13790-39-1 structure

13790-39-1

~%

171745-13-4 structure

171745-13-4

Literature: Bridges; Zhou; Cody; Rewcastle; McMichael; Showalter; Fry; Kraker; Denny Journal of Medicinal Chemistry, 1996 , vol. 39, # 1 p. 267 - 276

5653-40-7 structure

5653-40-7

~%

171745-13-4 structure

171745-13-4

Literature: Bridges; Zhou; Cody; Rewcastle; McMichael; Showalter; Fry; Kraker; Denny Journal of Medicinal Chemistry, 1996 , vol. 39, # 1 p. 267 - 276

13794-72-4 structure

13794-72-4

~%

171745-13-4 structure

171745-13-4

Literature: Bridges; Zhou; Cody; Rewcastle; McMichael; Showalter; Fry; Kraker; Denny Journal of Medicinal Chemistry, 1996 , vol. 39, # 1 p. 267 - 276

591-19-5 structure

591-19-5

162363-46-4 structure

162363-46-4

~%

171745-13-4 structure

171745-13-4

Literature: Wright, Stephen W.; Hageman, David L.; McClure, Lester D.; Carlo, Anthony A.; Treadway, Judith L.; Mathiowetz, Alan M.; Withka, Jane M.; Bauer, Paul H. Bioorganic and Medicinal Chemistry Letters, 2001 , vol. 11, # 1 p. 17 - 21

Precursor 5
591-19-5 13790-39-1 5653-40-7 13794-72-4
162363-46-4
DownStream 0

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.