4-(3-bromoanilino)-6,7-diethoxyquinazoline

Modify Date: 2025-08-27 09:25:21

4-(3-bromoanilino)-6,7-diethoxyquinazoline Structure
4-(3-bromoanilino)-6,7-diethoxyquinazoline structure
 Common Name 4-(3-bromoanilino)-6,7-diethoxyquinazoline
CAS Number 171745-13-4 Molecular Weight 388.26
Density 1.4±0.1 g/cm3 Boiling Point 492.6±45.0 °C at 760 mmHg
Molecular Formula C18H18BrN3O2 Melting Point N/A
MSDS N/A Flash Point 251.7±28.7 °C

 Use of 4-(3-bromoanilino)-6,7-diethoxyquinazoline


EGFR-IN-80 (compound 30) is an EGFR inhibitor with a pIC50 of 10.6[1].

 Names

Name N-(3-bromophenyl)-6,7-diethoxyquinazolin-4-amine
Synonym More Synonyms

  Biological Activity

Description EGFR-IN-80 (compound 30) is an EGFR inhibitor with a pIC50 of 10.6[1].
Related Catalog
Target

EGFR:10.6 (pIC50)

References

[1]. Farhan Ahmad Pasha, et al. In silico QSAR studies of anilinoquinolines as EGFR inhibitors. J Mol Model. 2010 Feb;16(2):263-77.  

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 492.6±45.0 °C at 760 mmHg
Molecular Formula C18H18BrN3O2
Molecular Weight 388.26
Flash Point 251.7±28.7 °C
Exact Mass 387.058228
PSA 56.27000
LogP 5.14
Vapour Pressure 0.0±1.3 mmHg at 25°C
Index of Refraction 1.652
InChIKey YXOXHAUUTIOBDA-UHFFFAOYSA-N
SMILES CCOc1cc2ncnc(Nc3cccc(Br)c3)c2cc1OCC

 Safety Information

 Synthetic Route

3-Bromoaniline structure

3-Bromoaniline

CAS#:591-19-5

~%

4-(3-bromoanilino)-6,7-diethoxyquinazoline Structure

4-(3-bromoanili...

CAS#:171745-13-4

Literature: Bridges; Zhou; Cody; Rewcastle; McMichael; Showalter; Fry; Kraker; Denny Journal of Medicinal Chemistry, 1996 , vol. 39, # 1 p. 267 - 276
4-Chloro-6,7-dimethoxyquinazoline structure

4-Chloro-6,7-di...

CAS#:13790-39-1

~%

4-(3-bromoanilino)-6,7-diethoxyquinazoline Structure

4-(3-bromoanili...

CAS#:171745-13-4

Literature: Bridges; Zhou; Cody; Rewcastle; McMichael; Showalter; Fry; Kraker; Denny Journal of Medicinal Chemistry, 1996 , vol. 39, # 1 p. 267 - 276
2-Amino-4,5-dimethoxybenzoic acid structure

2-Amino-4,5-dim...

CAS#:5653-40-7

~%

4-(3-bromoanilino)-6,7-diethoxyquinazoline Structure

4-(3-bromoanili...

CAS#:171745-13-4

Literature: Bridges; Zhou; Cody; Rewcastle; McMichael; Showalter; Fry; Kraker; Denny Journal of Medicinal Chemistry, 1996 , vol. 39, # 1 p. 267 - 276
6,7-Dimethoxy-3,4-dihydroquinazoline-4-one structure

6,7-Dimethoxy-3...

CAS#:13794-72-4

~%

4-(3-bromoanilino)-6,7-diethoxyquinazoline Structure

4-(3-bromoanili...

CAS#:171745-13-4

Literature: Bridges; Zhou; Cody; Rewcastle; McMichael; Showalter; Fry; Kraker; Denny Journal of Medicinal Chemistry, 1996 , vol. 39, # 1 p. 267 - 276
3-Bromoaniline structure

3-Bromoaniline

CAS#:591-19-5

4-Chloro-6,7-diethoxyquinazoline structure

4-Chloro-6,7-di...

CAS#:162363-46-4

~%

4-(3-bromoanilino)-6,7-diethoxyquinazoline Structure

4-(3-bromoanili...

CAS#:171745-13-4

Literature: Wright, Stephen W.; Hageman, David L.; McClure, Lester D.; Carlo, Anthony A.; Treadway, Judith L.; Mathiowetz, Alan M.; Withka, Jane M.; Bauer, Paul H. Bioorganic and Medicinal Chemistry Letters, 2001 , vol. 11, # 1 p. 17 - 21

 Synonyms

compound 56
N-(3-Bromophenyl)-6,7-diethoxyquinazolin-4-amine
4-(3'-bromoanilino)-6,7-diethoxyquinazoline
4-(3-bromoanilino)-6,7-diethoxyquinazoline
4-quinazolinamine, N-(3-bromophenyl)-6,7-diethoxy-
N-(3-Bromophenyl)-6,7-diethoxy-4-quinazolinamine
4-[(3-bromophenyl)amino]-6,7-diethoxyquinazoline
(3-Bromophenyl)-(6,7-diethoxyquinazolin-4-yl)-amine
YXOXHAUUTIOBDA-UHFFFAOYSA
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.
Top Suppliers:I want be here

Get all suppliers and price by the below link:

4-(3-bromoanilino)-6,7-diethoxyquinazoline suppliers

4-(3-bromoanilino)-6,7-diethoxyquinazoline price

Related Compounds: More...
N-[4-(3-bromoanilino)-6-nitroquinazolin-7-yl]acetamide
169205-91-8
BPDQ
169205-87-2
N-(3-Bromophenyl)-6-fluoropyrido[3,2-d]pyrimidin-4-amine
171178-22-6
4-(3,4,6,7,12,12a-hexahydropyrazino[1',2':1,6]pyrido[3,4-b]indol-2(1H)-yl)-1-phenylbutan-1-one
42021-39-6
4-(3,4,6,7,12,12a-hexahydropyrazino[1',2':1,6]pyrido[3,4-b]indol-2(1H)-yl)butan-2-one
42021-45-4
4-(3,4,6,7,12,12a-hexahydropyrazino[1',2':1,6]pyrido[3,4-b]indol-2(1H)-yl)-2-phenylbutan-2-ol
42021-52-3
4-(3,4,6,7,12,12a-hexahydropyrazino[1',2':1,6]pyrido[3,4-b]indol-2(1H)-yl)-1-(p-tolyl)butan-1-one
42021-42-1
4-(3,4,6,7,8,8a-hexahydro-1H-pyrrolo[1,2-a]pyrazin-2-yl)aniline
937607-36-8
4-(3,4,6,7,8,8a-hexahydro-1H-pyrrolo[1,2-a]pyrazin-2-yl)butan-2-one
88327-70-2
3-[2-Chloro-6-(trifluoromethyl)phenyl]-2,2-dimethylpropan-1-ol
2228569-10-4
2-[4-(Difluoromethoxy)-2-fluorophenyl]propan-2-ol
2228801-53-2
2-[3-Chloro-4-(trifluoromethoxy)phenyl]-2-methyloxirane
2228292-63-3
2,2-Dimethyl-3-(5-methyl-1,2-oxazol-4-yl)propan-1-amine
2228604-18-8
2-(1-methyl-1H-indazol-3-yl)propanal
2228683-57-4
5-(2-Ethylphenyl)-1,2-oxazole-3-carboxylic acid
2228340-04-1
2-[3-Methoxy-5-(methoxymethyl)-2-methylpyridin-4-yl]ethan-1-ol
2228319-14-8
Dipyrrolo[3,4-b:3a(2),4a(2)-c]pyrrole-2,7(1H,8H)-dicarboxylic acid, hexahydro-, 2-(1,1-dimethylethyl) 7-(phenylmethyl) ester, (3aR,5aS,8aS)-rel-
1251008-97-5
Propanoic acid, 2,3,3,3-tetrafluoro-2-[1,1,2,3,3,3-hexafluoro-2-(1,1,2,2,2-pentafluoroethoxy)propoxy]-, ammonium salt (1:1)
510774-79-5
1-(But-3-yn-1-yl)-2,4,5-trimethoxybenzene
2228470-48-0
Chemsrc provides CAS#:171745-13-4 MSDS, density, melting point, boiling point, structure, etc. Its name is 4-(3-bromoanilino)-6,7-diethoxyquinazoline>> amp version: 4-(3-bromoanilino)-6,7-diethoxyquinazoline

Home | MSDS/SDS Database Search | Journals | Product Classification | Biologically Active Compounds | Selling Leads | About Us | Disclaimer

Copyright © 2024 ChemSrc All Rights Reserved