1020720-04-0
1020720-04-0 structure
- Name: Zonisamide-d4
- Chemical Name: (4,5,6,7-tetradeuterio-1,2-benzoxazol-3-yl)methanesulfonamide
- CAS Number: 1020720-04-0
- Molecular Formula: C8H4D4N2O3S
- Molecular Weight: 216.25000
- Catalog: Signaling Pathways Membrane Transporter/Ion Channel Calcium Channel
- Create Date: 2016-12-20 15:11:31
- Modify Date: 2024-01-10 17:51:52
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Zonisamide-d4 (AD 810-d4) is the deuterium labeled Zonisamide. Zonisamide (AD 810) is an inhibitor of zinc enzyme carbonic anhydrase (CA), with Kis of 35.2 nM and 20.6 nM for human mitochondrial isozyme hCA II and hCA V, respectively. Zonisamide has antiepileptic activity. Zonisamide can be used for the rsearch for epilepsy, seizures and Parkinson's disease[1][2].
| Name | (4,5,6,7-tetradeuterio-1,2-benzoxazol-3-yl)methanesulfonamide |
|---|---|
| Synonyms |
Excegran-d4
Zonegran-d4 1,2-(Benzisoxazole-d4)-3-methanesulfonamide AD 810-d4 Zonisamide-d4 Aleviatin-d4 3-(Sulfamoylmethyl)-1,2-benzisoxazole-d4 |
| Description | Zonisamide-d4 (AD 810-d4) is the deuterium labeled Zonisamide. Zonisamide (AD 810) is an inhibitor of zinc enzyme carbonic anhydrase (CA), with Kis of 35.2 nM and 20.6 nM for human mitochondrial isozyme hCA II and hCA V, respectively. Zonisamide has antiepileptic activity. Zonisamide can be used for the rsearch for epilepsy, seizures and Parkinson's disease[1][2]. |
|---|---|
| Related Catalog | |
| In Vitro | Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1]. |
| References |
| Molecular Formula | C8H4D4N2O3S |
|---|---|
| Molecular Weight | 216.25000 |
| Exact Mass | 216.05100 |
| PSA | 94.57000 |
| LogP | 2.39740 |