1456699-27-6

1456699-27-6 structure

Name: TCMCB07
Chemical Name: D-Prolinamide, N-acetyl-L-norleucyl-L-α-aspartyl-L-prolyl-3-(2-naphthalenyl)-D-alanyl-L-arginyl-L-tryptophyl-L-lysyl-D-valyl-, (2→7)-lactam
CAS Number: 1456699-27-6
Molecular Formula: C₆₃H₈₇N₁₅O₁₁
Molecular Weight: 1230.46
Catalog: Research Areas Metabolic Disease
Create Date: 2024-01-08 21:59:58
Modify Date: 2024-01-08 21:59:58
TCMCB07, a cyclic nonapeptide peptide, is an orally active and brain-penetrant melanocortin receptor 4 (MC4R) antagonist. TCMCB07 plays an important role in cachexia[1].

Name	D-Prolinamide, N-acetyl-L-norleucyl-L-α-aspartyl-L-prolyl-3-(2-naphthalenyl)-D-alanyl-L-arginyl-L-tryptophyl-L-lysyl-D-valyl-, (2→7)-lactam

Description	TCMCB07, a cyclic nonapeptide peptide, is an orally active and brain-penetrant melanocortin receptor 4 (MC4R) antagonist. TCMCB07 plays an important role in cachexia[1].
Related Catalog	Research Areas >> Metabolic Disease Signaling Pathways >> GPCR/G Protein >> Melanocortin Receptor
References	[1]. Yongjun Hu, et al. Characterization of the cellular transport mechanisms for the anti-cachexia candidate compound TCMCB07. J Cachexia Sarcopenia Muscle. 2020 Dec;11(6):1677-1687.