126872-95-5

126872-95-5 structure

Name: Biphalin TFA
Chemical Name: Biphalin TFA
CAS Number: 126872-95-5
Molecular Formula: C₄₆H₅₆N₁₀O_10.xC₂HF₃O₂
Molecular Weight: 909.00 (free base)
Catalog: Signaling Pathways GPCR/G Protein Opioid Receptor
Create Date: 2023-12-26 19:34:27
Modify Date: 2024-01-30 22:15:56
Biphalin TFA, a BBB-penetrable opioid peptide analog, contains two active enkephalin pharmacophores. Biphalin TFA has high affinity for opioid receptors. Biphalin TFA shows analgesic effect in acute, neuropathic, and chronic animal pain models. Biphalin TFA is also an antiviral, antiproliferative, anti-inflammatory, and neuroprotective agent[1].

Name	Biphalin TFA

Description	Biphalin TFA, a BBB-penetrable opioid peptide analog, contains two active enkephalin pharmacophores. Biphalin TFA has high affinity for opioid receptors. Biphalin TFA shows analgesic effect in acute, neuropathic, and chronic animal pain models. Biphalin TFA is also an antiviral, antiproliferative, anti-inflammatory, and neuroprotective agent[1].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> Opioid Receptor Signaling Pathways >> Neuronal Signaling >> Opioid Receptor Research Areas >> Neurological Disease
References	[1]. T J Abbruscato, et al. Blood-to-central nervous system entry and stability of biphalin, a unique double-enkephalin analog, and its halogenated derivatives. J Pharmacol Exp Ther. 1996, 276,3. [2]. Redkiewicz P, et al. Biphalin-A Potent Opioid Agonist-As a Panacea for Opioid System-Dependent Pathophysiological Diseases? Int J Mol Sci. 2021 Oct 21;22(21):11347.

Molecular Formula	C₄₆H₅₆N₁₀O_10.xC₂HF₃O₂
Molecular Weight	909.00 (free base)

RIDADR	NONH for all modes of transport