1527479-55-5

1527479-55-5 structure

Name: Cobitolimod sodium
Chemical Name: Cobitolimod sodium
CAS Number: 1527479-55-5
Molecular Formula: C₁₈₅H₂₁₅N₇₃O₁₀₅P₁₈S₆Na₁₈
Molecular Weight: 6320.80
Catalog: Signaling Pathways Immunology/Inflammation Toll-like Receptor (TLR)
Create Date: 2023-12-22 16:55:56
Modify Date: 2024-03-06 02:58:05
Cobitolimod sodium is a DNA oligonucleotide agonist of TLR-9 with anti-inflammatory activity. Cobitolimod sodium inhibits Th17 cells and induces anti-inflammatory FoxP3 and IL-10 expression, inhibiting the IL-17 signaling pathway[1].

Name	Cobitolimod sodium

Description	Cobitolimod sodium is a DNA oligonucleotide agonist of TLR-9 with anti-inflammatory activity. Cobitolimod sodium inhibits Th17 cells and induces anti-inflammatory FoxP3 and IL-10 expression, inhibiting the IL-17 signaling pathway[1].
Related Catalog	Signaling Pathways >> Immunology/Inflammation >> Toll-like Receptor (TLR) Research Areas >> Inflammation/Immunology
Target	TLR-9[1]
References	[1]. Schmitt H, Ulmschneider J, Billmeier U, Vieth M, Scarozza P, Sonnewald S, Reid S, Atreya I, Rath T, Zundler S, Langheinrich M, Schüttler J, Hartmann A, Winkler T, Admyre C, Knittel T, Dieterich Johansson C, Zargari A, Neurath MF, Atreya R. The TLR9 Agonist Cobitolimod Induces IL10-Producing Wound Healing Macrophages and Regulatory T Cells in Ulcerative Colitis. J Crohns Colitis. 2020 May 21;14(4):508-524.

Molecular Formula	C₁₈₅H₂₁₅N₇₃O₁₀₅P₁₈S₆Na₁₈
Molecular Weight	6320.80