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1782098-79-6

1782098-79-6 structure

1782098-79-6 structure

Name: Cyclorasin 9A5
Chemical Name: Cyclorasin 9A5
CAS Number: 1782098-79-6
Molecular Formula: C₇₅H₁₀₈FN₂₅O₁₃
Molecular Weight: 1586.82
Catalog: Signaling Pathways GPCR/G Protein Ras
Create Date: 2023-12-31 11:37:54
Modify Date: 2024-01-07 10:56:26
Cyclorasin 9A5 is an 11-residue cell-permeable cyclic peptide that orthosterically inhibits the Ras-Raf protein interaction with an IC50 of 120 nM[1].

Name	Cyclorasin 9A5

Description	Cyclorasin 9A5 is an 11-residue cell-permeable cyclic peptide that orthosterically inhibits the Ras-Raf protein interaction with an IC50 of 120 nM[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> GPCR/G Protein >> Ras Signaling Pathways >> MAPK/ERK Pathway >> Raf
Target	IC50: 120 nM (Ras-Raf protein interaction)[1].
References	[1]. Koh Takeuchi, et al. Conformational Plasticity of Cyclic Ras-Inhibitor Peptides Defines Cell Permeabilization Activity. Angew Chem Int Ed Engl. 2021 Mar 15;60(12):6567-6572.

Molecular Formula	C₇₅H₁₀₈FN₂₅O₁₃
Molecular Weight	1586.82

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