Cyclorasin 9A5

Modify Date: 2025-09-23 15:58:02

Cyclorasin 9A5 structure	Common Name	Cyclorasin 9A5
	CAS Number	1782098-79-6	Molecular Weight	1586.82
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₇₅H₁₀₈FN₂₅O₁₃	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Cyclorasin 9A5

Cyclorasin 9A5 is an 11-residue cell-permeable cyclic peptide that orthosterically inhibits the Ras-Raf protein interaction with an IC50 of 120 nM[1].

Name	Cyclorasin 9A5

Description	Cyclorasin 9A5 is an 11-residue cell-permeable cyclic peptide that orthosterically inhibits the Ras-Raf protein interaction with an IC50 of 120 nM[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> GPCR/G Protein >> Ras Signaling Pathways >> MAPK/ERK Pathway >> Raf
Target	IC50: 120 nM (Ras-Raf protein interaction)[1].
References	[1]. Koh Takeuchi, et al. Conformational Plasticity of Cyclic Ras-Inhibitor Peptides Defines Cell Permeabilization Activity. Angew Chem Int Ed Engl. 2021 Mar 15;60(12):6567-6572.

Molecular Formula	C₇₅H₁₀₈FN₂₅O₁₃
Molecular Weight	1586.82

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