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1799330-91-8

1799330-91-8 structure

1799330-91-8 structure

Name: LFS-1107
Chemical Name: LFS-1107
CAS Number: 1799330-91-8
Molecular Formula: C₁₂H₁₁N₅OS₂
Molecular Weight: 305.38
Catalog: Signaling Pathways Apoptosis c-Myc
Create Date: 2023-12-21 17:31:46
Modify Date: 2026-07-28 20:37:42
LFS-1107 is a reversible CRM1 inhibitor (Kd: 12.5 pM). LFS-1107 can selectively eliminate extranodal natural killer/T cell lymphoma (ENKTL) cells and can be used for cancer research[1].

Name	LFS-1107
Synonyms	1H-Tetrazole, 5-[(4-isothiocyanato-1-buten-1-yl)sulfinyl]-1-phenyl

Description	LFS-1107 is a reversible CRM1 inhibitor (Kd: 12.5 pM). LFS-1107 can selectively eliminate extranodal natural killer/T cell lymphoma (ENKTL) cells and can be used for cancer research[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Apoptosis >> Survivin Signaling Pathways >> Membrane Transporter/Ion Channel >> CRM1 Signaling Pathways >> Apoptosis >> c-Myc Signaling Pathways >> Immunology/Inflammation >> COX
Target	COX-2
References	[1]. He Liu, et al. Discovery and biological evaluation of a potent small molecule CRM1 inhibitor for its selective ablation of extranodal NK/T cell lymphoma eLife 12:e80625.

Molecular Formula	C₁₂H₁₁N₅OS₂
Molecular Weight	305.38

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