38470-71-2

38470-71-2 structure

Name: MAO-B-IN-26
Chemical Name: MAO-B-IN-26
CAS Number: 38470-71-2
Molecular Formula: C₁₇H₁₂BrNO
Molecular Weight: 326.19
Catalog: Signaling Pathways Apoptosis Apoptosis
Create Date: 2024-01-23 17:49:01
Modify Date: 2024-01-23 17:49:01
MAO-B-IN-26 (Compound IC9) is a MAO-B and acetylcholinesterase inhibitor. MAO-B-IN-26 protects SH?SY5Y cells against Aβ induced cytotoxicity, morphological changes, ROS generation and membrane damage. MAO-B-IN-26 also inhibits Aβ induced autophagy and apoptosis. MAO-B-IN-26 can be used as a neuroprotective agent against Alzheimer’s disease[1].

Name	MAO-B-IN-26

Description	MAO-B-IN-26 (Compound IC9) is a MAO-B and acetylcholinesterase inhibitor. MAO-B-IN-26 protects SH?SY5Y cells against Aβ induced cytotoxicity, morphological changes, ROS generation and membrane damage. MAO-B-IN-26 also inhibits Aβ induced autophagy and apoptosis. MAO-B-IN-26 can be used as a neuroprotective agent against Alzheimer’s disease[1].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Signaling Pathways >> Neuronal Signaling >> Monoamine Oxidase Signaling Pathways >> Autophagy >> Autophagy Research Areas >> Neurological Disease Signaling Pathways >> Neuronal Signaling >> AChE
References	[1]. Sasidharan R, et al. MAO-B Inhibitor (2E)-3-(4-Bromophenyl)-1-(1H-indol-3-yl) prop-2-en-1-one as a Neuroprotective Agent Against Alzheimer's Disease. Neurochem Res. 2023 Oct 9.

Molecular Formula	C₁₇H₁₂BrNO
Molecular Weight	326.19