2454019-69-1

2454019-69-1 structure

Name: NLRP3 agonist 1
Chemical Name: NLRP3 agonist 1
CAS Number: 2454019-69-1
Molecular Formula: C₁₅H₁₆N₆
Molecular Weight: 280.33
Catalog: Signaling Pathways Immunology/Inflammation NOD-like Receptor (NLR)
Create Date: 2024-01-13 23:19:55
Modify Date: 2024-01-13 23:19:55
NLRP3 agonist 1 (compound 23) is a potent and orally active NLRP3 agonist. NLRP3 agonist 1 can activate the enzyme Caspase-1 to cleave pro-IL-1β and pro-IL-18 proinflammatory cytokines into their mature forms[1].

Name	NLRP3 agonist 1

Description	NLRP3 agonist 1 (compound 23) is a potent and orally active NLRP3 agonist. NLRP3 agonist 1 can activate the enzyme Caspase-1 to cleave pro-IL-1β and pro-IL-18 proinflammatory cytokines into their mature forms[1].
Related Catalog	Signaling Pathways >> Immunology/Inflammation >> NOD-like Receptor (NLR) Research Areas >> Inflammation/Immunology
References	[1]. O' Donovan DH, et, al. Discovery and characterisation of quinazolines and 8-Azaquinazolines as NLRP3 agonists with oral bioavailability in mice. Bioorg Med Chem Lett. 2023 Oct 12:96:129518.

Molecular Formula	C₁₅H₁₆N₆
Molecular Weight	280.33