2956791-61-8

2956791-61-8 structure

Name: NLRP3-IN-21
Chemical Name: NLRP3-IN-21
CAS Number: 2956791-61-8
Molecular Formula: C₂₀H₁₃Cl₂F₃N₆O₂S
Molecular Weight: 529.32
Catalog: Signaling Pathways Immunology/Inflammation NOD-like Receptor (NLR)
Create Date: 2023-12-22 12:07:23
Modify Date: 2024-01-14 03:44:28
NLRP3-IN-21 (compound L38) is a NLRP3 inflammasome inhibitor with inflammatory properties. NLRP3-IN-21 inhibits NLRP3 inflammasome activation and pyroptosis by suppressing gasdermin D cleavage, ASC oligomerization, and NLRP3 inflammasome assembly[1].

Name	NLRP3-IN-21

Description	NLRP3-IN-21 (compound L38) is a NLRP3 inflammasome inhibitor with inflammatory properties. NLRP3-IN-21 inhibits NLRP3 inflammasome activation and pyroptosis by suppressing gasdermin D cleavage, ASC oligomerization, and NLRP3 inflammasome assembly[1].
Related Catalog	Signaling Pathways >> Immunology/Inflammation >> NOD-like Receptor (NLR) Research Areas >> Inflammation/Immunology
References	[1]. Na Li, et al. Discovery of Triazinone Derivatives as Novel, Specific, and Direct NLRP3 Inflammasome Inhibitors for the Treatment of DSS-Induced Ulcerative Colitis. J Med Chem. 2023 Oct 12;66(19):13428-13451.

Molecular Formula	C₂₀H₁₃Cl₂F₃N₆O₂S
Molecular Weight	529.32