2195434-05-8

2195434-05-8 structure

Name: OAT1/3-IN-2
Chemical Name: OAT1/3-IN-2
CAS Number: 2195434-05-8
Molecular Formula: C₁₈H₁₆O₆
Molecular Weight: 328.32
Catalog: Research Areas Metabolic Disease
Create Date: 2024-02-06 12:20:58
Modify Date: 2025-08-25 18:41:05
OAT1/3-IN-2 (compound 8) is a dual inhibitor of OAT1 and OAT3. OAT1/3-IN-2 can reverse the toxicity of Cys-Hg on HEK-OAT1 cells (10 μM) and has a potential protective effect on the kidneys. OAT1/3-IN-2 can be used to study mercury-induced kidney damage[1].

Name	OAT1/3-IN-2

Description	OAT1/3-IN-2 (compound 8) is a dual inhibitor of OAT1 and OAT3. OAT1/3-IN-2 can reverse the toxicity of Cys-Hg on HEK-OAT1 cells (10 μM) and has a potential protective effect on the kidneys. OAT1/3-IN-2 can be used to study mercury-induced kidney damage[1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Metabolic Disease
Target	Organic anion transporter 1 and 3 (OAT1 and OAT3)[1]
References	[1]. Wang X, et al. From the Cover: Identification of Natural Products as Inhibitors of Human Organic Anion Transporters (OAT1 and OAT3) and Their Protective Effect on Mercury-Induced Toxicity. Toxicol Sci. 2018 Feb 1;161(2):321-334.

Molecular Formula	C₁₈H₁₆O₆
Molecular Weight	328.32