2639372-47-5

2639372-47-5 structure
2639372-47-5 structure
  • Name: PF-07202954
  • Chemical Name: PF-07202954
  • CAS Number: 2639372-47-5
  • Molecular Formula: C22H23FN6O3
  • Molecular Weight: 438.45
  • Catalog: Research Areas Metabolic Disease
  • Create Date: 2024-01-13 15:05:07
  • Modify Date: 2024-01-13 15:05:07
  • PF-07202954 is a weakly basic DGAT2 inhibitor with an IC50 of 10 nM for human DGAT2. PF-07202954 lowers liver triglyceride content in a Western-diet-fed rat model[1].

Name PF-07202954
Description PF-07202954 is a weakly basic DGAT2 inhibitor with an IC50 of 10 nM for human DGAT2. PF-07202954 lowers liver triglyceride content in a Western-diet-fed rat model[1].
Related Catalog
References

[1]. Kevin J Filipski, et al. Design of Next-Generation DGAT2 Inhibitor PF-07202954 with Longer Predicted Half-Life. ACS Med Chem Lett. 2023 Oct 2;14(10):1427-1433.  

Molecular Formula C22H23FN6O3
Molecular Weight 438.45
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