2919684-77-6

2919684-77-6 structure
2919684-77-6 structure
  • Name: PI3K/mTOR Inhibitor-14
  • Chemical Name: PI3K/mTOR Inhibitor-14
  • CAS Number: 2919684-77-6
  • Molecular Formula: C28H30N8O3S
  • Molecular Weight: 558.65
  • Catalog: Signaling Pathways PI3K/Akt/mTOR mTOR
  • Create Date: 2023-12-26 19:42:46
  • Modify Date: 2024-01-07 19:30:04
  • PI3K/mTOR Inhibitor-14 (compound Y-2) is a potent PI3K and mTOR dual inhibitor with IC50s of 171.4 nM and 10.1 nM, respectively. PI3K/mTOR Inhibitor-14 has antitumor activities[1].

Name PI3K/mTOR Inhibitor-14
Description PI3K/mTOR Inhibitor-14 (compound Y-2) is a potent PI3K and mTOR dual inhibitor with IC50s of 171.4 nM and 10.1 nM, respectively. PI3K/mTOR Inhibitor-14 has antitumor activities[1].
Related Catalog
Target

PI3K:171.4 nM (IC50)

mTOR:10.1 nM (IC50)

References

[1]. Yang Yang, et al. Discovery of novel potent PI3K/mTOR dual-target inhibitors based on scaffold hopping: Design, synthesis, and antiproliferative activity. Arch Pharm (Weinheim). 2023 Oct 15:e2300403.  

Molecular Formula C28H30N8O3S
Molecular Weight 558.65
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