PI3K/mTOR Inhibitor-14

Modify Date: 2024-01-07 19:30:04

PI3K/mTOR Inhibitor-14 Structure
PI3K/mTOR Inhibitor-14 structure
Common Name PI3K/mTOR Inhibitor-14
CAS Number 2919684-77-6 Molecular Weight 558.65
Density N/A Boiling Point N/A
Molecular Formula C28H30N8O3S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of PI3K/mTOR Inhibitor-14


PI3K/mTOR Inhibitor-14 (compound Y-2) is a potent PI3K and mTOR dual inhibitor with IC50s of 171.4 nM and 10.1 nM, respectively. PI3K/mTOR Inhibitor-14 has antitumor activities[1].

 Names

Name PI3K/mTOR Inhibitor-14

 PI3K/mTOR Inhibitor-14 Biological Activity

Description PI3K/mTOR Inhibitor-14 (compound Y-2) is a potent PI3K and mTOR dual inhibitor with IC50s of 171.4 nM and 10.1 nM, respectively. PI3K/mTOR Inhibitor-14 has antitumor activities[1].
Related Catalog
Target

PI3K:171.4 nM (IC50)

mTOR:10.1 nM (IC50)

References

[1]. Yang Yang, et al. Discovery of novel potent PI3K/mTOR dual-target inhibitors based on scaffold hopping: Design, synthesis, and antiproliferative activity. Arch Pharm (Weinheim). 2023 Oct 15:e2300403.  

 Chemical & Physical Properties

Molecular Formula C28H30N8O3S
Molecular Weight 558.65