2929304-61-8
2929304-61-8 structure
- Name: UNC8153 TFA
- Chemical Name: UNC8153 TFA
- CAS Number: 2929304-61-8
- Molecular Formula: C35H38F3N5O7
- Molecular Weight: 697.70
- Catalog: Signaling Pathways Epigenetics Histone Methyltransferase
- Create Date: 2024-01-08 14:03:47
- Modify Date: 2025-08-25 17:19:18
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UNC8153 TFA is a potent and selective nuclear receptor-binding SET domain-containing 2 (NSD2)-targeted degrader with a Kd of 24 nM. UNC8153 TFA reduces the cellular levels of both NSD2 protein and the H3K36me2 chromatin mark. UNC8153 TFA contains a simple warhead that confers proteasome-dependent degradation of NSD2[1].
| Name | UNC8153 TFA |
|---|
| Description | UNC8153 TFA is a potent and selective nuclear receptor-binding SET domain-containing 2 (NSD2)-targeted degrader with a Kd of 24 nM. UNC8153 TFA reduces the cellular levels of both NSD2 protein and the H3K36me2 chromatin mark. UNC8153 TFA contains a simple warhead that confers proteasome-dependent degradation of NSD2[1]. |
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| Molecular Formula | C35H38F3N5O7 |
|---|---|
| Molecular Weight | 697.70 |