Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Palmitic acid
Price: Check
Purity: 98.0%
Stocking Period: 10 Day
Contact: Yang
Email: sales@echemcloud.com

2470908-90-6

2470908-90-6 structure

2470908-90-6 structure

Name: YS-363
Chemical Name: YS-363
CAS Number: 2470908-90-6
Molecular Formula: C₃₀H₃₀N₄O₃
Molecular Weight: 494.58
Catalog: Signaling Pathways Apoptosis Apoptosis
Create Date: 2024-03-10 18:11:44
Modify Date: 2024-03-10 18:11:44
YS-363 is a potent, selective, and orally active EGFR inhibitor, with IC50s of 0.96 nM and 0.67 nM for wild-type and L858R mutant forms of EGFR, respectively. YS-363 can induce G0/G1 cell cycle arrest and apoptosis[1].

Name	YS-363

Description	YS-363 is a potent, selective, and orally active EGFR inhibitor, with IC50s of 0.96 nM and 0.67 nM for wild-type and L858R mutant forms of EGFR, respectively. YS-363 can induce G0/G1 cell cycle arrest and apoptosis[1].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer Signaling Pathways >> JAK/STAT Signaling >> EGFR Signaling Pathways >> Protein Tyrosine Kinase/RTK >> EGFR
Target	EGFR:0.96 nM (IC50)
References	[1]. He P, et, al. Discovery of YS-363 as a highly potent, selective, and orally eﬃcacious EGFR inhibitor. Biomed Pharmacother. 2023 Nov:167:115491.

Molecular Formula	C₃₀H₃₀N₄O₃
Molecular Weight	494.58

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.