869718-81-0

869718-81-0 structure

Name: m-PEG8-Amine
Chemical Name: 2-[2-[2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanamine
CAS Number: 869718-81-0
Molecular Formula: C₁₇H₃₇NO₈
Molecular Weight: 383.47800
Catalog: Signaling Pathways Antibody-drug Conjugate ADC Linker
Create Date: 2018-12-27 19:14:26
Modify Date: 2024-01-04 10:54:19
m-PEG8-Amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

Name	2-[2-[2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanamine
Synonyms	3,6,9,12,15,18,21,24-OCTAOXAPENTACOSAN-1-AMINE AmbotzPEG1700

Description	m-PEG8-Amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker
Target	Cleavable
In Vitro	ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
References	[1]. Joshua D. Thoma, et al. Pyrrolobenzodiazepine antibody conjugates. WO2019126691A1.

Density	1.054
Boiling Point	448ºC at 760 mmHg
Molecular Formula	C₁₇H₃₇NO₈
Molecular Weight	383.47800
Flash Point	213.9ºC
Exact Mass	383.25200
PSA	99.86000
LogP	0.40800
Storage condition	-20 °C

Hazard Codes	Xi

869718-80-9

~92%

869718-81-0

Literature: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA; THE CALIFORNIA INSTITUTE OF TECHNOLOGY Patent: WO2005/110397 A1, 2005 ; Location in patent: Page/Page column 31-32 ;

869718-80-9

~90%

869718-81-0

Literature: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA; THE CALIFORNIA INSTITUTE OF TECHNOLOGY Patent: WO2005/110397 A1, 2005 ; Location in patent: Page/Page column 31-32 ;

Precursor 1
869718-80-9
DownStream 0

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