99-43-4

99-43-4 structure

99-43-4 structure

Name: Oxybuprocaine
Chemical Name: oxybuprocaine
CAS Number: 99-43-4
Molecular Formula: C₁₇H₂₈N₂O₃
Molecular Weight: 308.41600
Catalog: API Anesthetic Agents Local anesthetics
Create Date: 2018-05-31 08:00:00
Modify Date: 2024-01-09 07:08:53
Oxybuprocaine is a short-acting ester-type local anesthetic agent used in ophthalmology and otolaryngology[1].

Name	oxybuprocaine
Synonyms	Benoxinate Oxybuprocaine Oxybucaine Prescaina Oxibuprocainum Conjucain 2-(Diethylamino)ethyl 4-amino-3-butoxybenzoate 4-Amino-3-butoxy-benzoesaeure-(2-diaethylamino-aethylester) 4-amino-3-butoxy-benzoic acid-(2-diethylamino-ethyl ester) Benoxil Oxibuprocaina Oxibuprokain Oxyriprocaine

Description	Oxybuprocaine is a short-acting ester-type local anesthetic agent used in ophthalmology and otolaryngology[1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology
References	[1]. Masayuki Kohsaka, et al. Oxybuprocaine for apraxia of lid opening in Parkinson's disease: A placebo-controlled pilot trial. Mov Disord

Density	1.052g/cm3
Boiling Point	446.9ºC at 760mmHg
Molecular Formula	C₁₇H₂₈N₂O₃
Molecular Weight	308.41600
Flash Point	224.1ºC
Exact Mass	308.21000
PSA	64.79000
LogP	3.52750
Index of Refraction	1.524

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DG1502000

CHEMICAL NAME :: Benzoic acid, 4-amino-3-butoxy-, 2-(diethylamino)ethyl ester

CAS REGISTRY NUMBER :: 99-43-4

BEILSTEIN REFERENCE NO. :: 2288926

LAST UPDATED :: 199612

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C17-H28-N2-O3

MOLECULAR WEIGHT :: 308.47

WISWESSER LINE NOTATION :: 4OR BZ EVO2N2&2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 37 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AACRAT Anesthesia and Analgesia (New York). (Elsevier Science Pub. Co., Inc., 52 Vanderbilt Ave., New York, NY 10017) V.36- 1957- Volume(issue)/page/year: 38,265,1959

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 75 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AACRAT Anesthesia and Analgesia (New York). (Elsevier Science Pub. Co., Inc., 52 Vanderbilt Ave., New York, NY 10017) V.36- 1957- Volume(issue)/page/year: 38,265,1959

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 7800 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 3,612,1953

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Bird - quail

DOSE/DURATION :: 100 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: EESADV Ecotoxicology and Environmental Safety. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1977- Volume(issue)/page/year: 6,149,1982

HS Code	2922509090

72101-53-2 structure

72101-53-2

100-37-8 structure

100-37-8

~%

99-43-4 structure

99-43-4

Literature: Helvetica Chimica Acta, , vol. 34, p. 1002,1008,1010

Precursor 2
72101-53-2 100-37-8
DownStream 1
23442-22-0

HS Code	2922509090
Summary	2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%