6640-90-0

6640-90-0 structure

Name: 4-tert-butyl-2-((cyclohexylamino)methyl)-6-methylphenol
Chemical Name: 4-tert-butyl-2-[(cyclohexylamino)methyl]-6-methylphenol
CAS Number: 6640-90-0
Molecular Formula: C₁₈H₂₉NO
Molecular Weight: 275.42900
Catalog: Signaling Pathways Apoptosis Apoptosis
Create Date: 2016-02-26 12:14:36
Modify Date: 2024-01-09 18:33:16
NSC 48160 inhibits the growth of the pancreatic cancer cells with IC50s of 84.3 μM for CPFAC-1 and 94.5 μM for BxPC-3. NSC 48160 also induces pancreatic cancer cell apoptosis. NSC 48160 can improve metabolic syndromes, such as NASH, obesity and lipid metabolism disorders[1][2].

Name	4-tert-butyl-2-[(cyclohexylamino)methyl]-6-methylphenol
Synonyms	4-tert-Butyl-2-cyclohexylaminomethyl-6-methyl-phenol

Description	NSC 48160 inhibits the growth of the pancreatic cancer cells with IC50s of 84.3 μM for CPFAC-1 and 94.5 μM for BxPC-3. NSC 48160 also induces pancreatic cancer cell apoptosis. NSC 48160 can improve metabolic syndromes, such as NASH, obesity and lipid metabolism disorders[1][2].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer
References	[1]. Li D, et al. A small-molecule induces apoptosis and suppresses metastasis in pancreatic cancer cells. Eur J Pharm Sci. 2013 Mar 12;48(4-5):658-67. [2]. Liu zuijia, et al. Application of small molecule compound NSC48160 in preparation of medicine for treating non-alcoholic fatty liver disease. Patent. CN115869292

101887-94-9

6640-90-0

Literature: Burke et al. Journal of the American Chemical Society, 1958 , vol. 80, p. 3438,3443

108-91-8

6640-90-0

Literature: Burke et al. Journal of the American Chemical Society, 1958 , vol. 80, p. 3438,3443

50-00-0

98-27-1

108-91-8

6640-90-0

Literature: Burke et al. Journal of the American Chemical Society, 1958 , vol. 80, p. 3438,3443

Precursor 3
108-91-8 50-00-0 98-27-1
DownStream 0