41880-59-5

41880-59-5 structure

Name: Glp-His-Pro-Gly-NH2
Chemical Name: (2S)-N-[(2S)-1-[(2S)-2-[(2-amino-2-oxoethyl)carbamoyl]pyrrolidin-1-yl]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]-5-oxopyrrolidine-2-carboxamide
CAS Number: 41880-59-5
Molecular Formula: C₁₈H₂₅N₇O₅
Molecular Weight: 419.43500
Catalog: Research Areas Endocrinology
Create Date: 2016-01-19 09:47:04
Modify Date: 2024-01-13 21:51:53
Glp-His-Pro-Gly-NH2 (pGlu-His-Pro-Gly-NH2) is a peptide containing 4 amino acids. Glp-His-Pro-Gly-NH2 stimulates gonadotrophin, luteinizing hormone (LH) and follicle stimulating hormone (FSH) release[1][2].

Name	(2S)-N-[(2S)-1-[(2S)-2-[(2-amino-2-oxoethyl)carbamoyl]pyrrolidin-1-yl]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]-5-oxopyrrolidine-2-carboxamide
Synonyms	Glycinamide,5-oxo-L-prolyl-L-histidyl-L-prolyl pGlu-His-Pro-Gly-NH2

Description	Glp-His-Pro-Gly-NH2 (pGlu-His-Pro-Gly-NH2) is a peptide containing 4 amino acids. Glp-His-Pro-Gly-NH2 stimulates gonadotrophin, luteinizing hormone (LH) and follicle stimulating hormone (FSH) release[1][2].
Related Catalog	Research Areas >> Endocrinology Signaling Pathways >> Others >> Others
In Vitro	Glp-His-Pro-Gly-NH2 (pGlu-His-Pro-Gly-NH2; 6.6 μg/mL; 人胎儿垂体) 分别诱导黄体生成素 (LH) 和卵泡刺激素 (FSH) 释放 85% 和 96%[2]。
References	[1]. Visser TJ, et, al. A new radioimmunoassay of thyrotropin-releasing hormone. FEBS Lett. 1977 Nov 1;83(1):37-40. [2]. Groom GV, et, al. Gonadotrophin release from human foetal pituitary cultures induced by fragments of the luteinizing hormone-releasing hormone. FEBS Lett. 1973 Jun 15;33(1):57-60.