Glp-His-Pro-Gly-NH2

Modify Date: 2024-01-13 21:51:53

Glp-His-Pro-Gly-NH2 Structure
Glp-His-Pro-Gly-NH2 structure
Common Name Glp-His-Pro-Gly-NH2
CAS Number 41880-59-5 Molecular Weight 419.43500
Density N/A Boiling Point N/A
Molecular Formula C18H25N7O5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Glp-His-Pro-Gly-NH2


Glp-His-Pro-Gly-NH2 (pGlu-His-Pro-Gly-NH2) is a peptide containing 4 amino acids. Glp-His-Pro-Gly-NH2 stimulates gonadotrophin, luteinizing hormone (LH) and follicle stimulating hormone (FSH) release[1][2].

 Names

Name (2S)-N-[(2S)-1-[(2S)-2-[(2-amino-2-oxoethyl)carbamoyl]pyrrolidin-1-yl]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]-5-oxopyrrolidine-2-carboxamide
Synonym More Synonyms

 Glp-His-Pro-Gly-NH2 Biological Activity

Description Glp-His-Pro-Gly-NH2 (pGlu-His-Pro-Gly-NH2) is a peptide containing 4 amino acids. Glp-His-Pro-Gly-NH2 stimulates gonadotrophin, luteinizing hormone (LH) and follicle stimulating hormone (FSH) release[1][2].
Related Catalog
In Vitro Glp-His-Pro-Gly-NH2 (pGlu-His-Pro-Gly-NH2; 6.6 μg/mL; 人胎儿垂体) 分别诱导黄体生成素 (LH) 和卵泡刺激素 (FSH) 释放 85% 和 96%[2]。
References

[1]. Visser TJ, et, al. A new radioimmunoassay of thyrotropin-releasing hormone. FEBS Lett. 1977 Nov 1;83(1):37-40.   

[2]. Groom GV, et, al. Gonadotrophin release from human foetal pituitary cultures induced by fragments of the luteinizing hormone-releasing hormone. FEBS Lett. 1973 Jun 15;33(1):57-60.  

 Chemical & Physical Properties

Molecular Formula C18H25N7O5
Molecular Weight 419.43500
Exact Mass 419.19200
PSA 190.84000
LogP 0.35220

 Synonyms

Glycinamide,5-oxo-L-prolyl-L-histidyl-L-prolyl
pGlu-His-Pro-Gly-NH2