1219803-48-1

1219803-48-1 structure

Name: Chlorotoluron-d6
Chemical Name: Chlorotoluron-d6
CAS Number: 1219803-48-1
Molecular Formula: C₁₀H₇ClD₆N₂O
Molecular Weight: 218.713
Catalog: Research Areas Others
Create Date: 2018-08-09 23:03:31
Modify Date: 2024-01-08 21:23:57
Chlorotoluron-d6 is the deuterium labeled Chlorotoluron[1]. Chlorotoluron (Chlortoluron) is a substituted phenylurea herbicide, is widely used for selective weed control in cereals crops and is an environmental pollutant[2].

Name	Chlorotoluron-d6
Synonyms	Urea, N'-(3-chloro-4-methylphenyl)-N,N-dimethyl-d- 3-(3-chloro-4-methylphenyl)-1,1-bis(trideuteriomethyl)urea 3-(3-Chloro-4-methylphenyl)-1,1-bis[(H)methyl]urea

Description	Chlorotoluron-d6 is the deuterium labeled Chlorotoluron[1]. Chlorotoluron (Chlortoluron) is a substituted phenylurea herbicide, is widely used for selective weed control in cereals crops and is an environmental pollutant[2].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [2]. Z Mehmood, et al. Metabolism of the Herbicide Chlortoluron by Human Cytochrome P450 3A4. Chemosphere. 1995 Dec;31(11-12):4515-29.